Ultrafast and absolute quantification of SARS-CoV-2 on food using hydrogel RT-LAMP without pre-lysisArticle Published on 2023-01-152022-11-16 Journal: Journal of hazardous materials [Category] SARS, 치료기술, [키워드] Absolute quantification acute respiratory syndrome amplification cold chain Cold chain food contact infection coronavirus faster Food industry hydrogel Hydrogel RT-LAMP isothermal amplification microbe offer POCT point-of-care quantification reproducibility reverse transcription RNA RNA extraction RT-LAMP SARS-CoV-2 sensitivity specificity stability Surveillance Ultrafast detection. virus [DOI] 10.1016/j.jhazmat.2022.130050 PMC 바로가기
Consensus Receptor-Binding Domain-Targeted Aptamer Selection and Designing of a Photonic Crystal-Decorated Aptasensor for SARS-CoV-2SARS-CoV-2에 대한 광자 결정 장식 압타센서의 합의 수용체 결합 도메인 표적 압타머 선택 및 설계Article Published on 2022-05-242022-09-11 Journal: Analytical Chemistry [Category] COVID19(2023년), SARS, 변종, 치료기술, 치료제, [키워드] amino acids aptamer binding Cell Consensus conserved crosslinked Diagnosis diffraction glycoprotein hydrogel in silico Approach loss of activity platform POCT point-of-care polyacrylamide polymerized polystyrene quantified rapid response RBD Receptor-binding domain S-protein Saliva saliva samples SARS-CoV-2 selected Selection sensor spectrometer ssDNA swelling the receptor-binding domain variants variants of concern virus mutations VoC [DOI] 10.1021/acs.analchem.2c00937 PMC 바로가기 [Article Type] Article
Membrane-Based In-Gel Loop-Mediated Isothermal Amplification (mgLAMP) System for SARS-CoV-2 Quantification in Environmental Waters환경 수역에서 SARS-CoV-2 정량화를 위한 막 기반 겔 루프 매개 등온 증폭(mgLAMP) 시스템Article Published on 2022-01-182022-09-11 Journal: Environmental science & technology [Category] SARS, 치료기술, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 ambient Analysis assays Chain Reaction Concentration Coronavirus-2 COVID-19 pandemic Critical Early detection Endemic environmental quantification of SARS-CoV-2 in milliliters of environmental water samples equipment expected fluorescence detection hydrogel Image processing inhibited Interpretation isothermal amplification labor-intensive LAMP less Loop-mediated isothermal amplification lowest membrane membrane. Milli-Q nine Outbreaks polymerase chain polymerase chain reaction probe quantification Quantitative reverse transcription reverse transcription quantitative polymerase chain reaction RT-LAMP RT-qPCR SARS-CoV-2 SARS-CoV-2 particle SARS-CoV-2 particles Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 Surface water Surveillance System water [DOI] 10.1021/acs.est.1c04623 PMC 바로가기 [Article Type] Article
Sustained Delivery of SARS-CoV-2 RBD Subunit Vaccine Using a High Affinity Injectable Hydrogel Scaffold고친화성 주사 가능한 하이드로겔 지지체를 사용한 SARS-CoV-2 RBD 소단위 백신의 지속 전달Article Published on 2022-01-012022-09-12 Journal: Advanced Healthcare Materials [Category] MERS, SARS, 진단, [키워드] Activation acute respiratory syndrome Administered affinity antibody approach cellular cellular immunity circulating comparable coronavirus coronavirus disease COVID-19 delivery demonstrated Efficacy effort elicit ENhance Germinal center host cell humoral Humoral immunity hydrogel induce Inflammatory injectable hydrogel scaffolds Injections innate immune cell Local long-lasting lymphoid tissues mice Pathogens Prolonged provide RBD Reactions Receptor binding Receptor binding domain robust SARS-CoV-2 SARS-CoV-2 RBD serum IgG severe acute respiratory syndrome coronavirus 2 receptor binding domain Spike protein Subunit vaccine sustained sustained release T cell responses Vaccine development Vaccines Vaccines. viral entry [DOI] 10.1002/adhm.202101714 PMC 바로가기 [Article Type] Article
Thermosensitive Poly(DHSe/PEG/PPG Urethane)-Based Hydrogel Extended Remdesivir Application in Ophthalmic MedicationArticle Published on 2021-12-272022-10-28 Journal: Pharmaceutics [Category] COVID-19, [키워드] acute respiratory syndrome application caused characterized conjunctival Corneal coronavirus coronavirus disease COVID-19 dose epithelial cells evaluated exhibited Extended eyes Final gel gelling glycol hydrogel in vivo indicated Infection lack Microscopy Novel coronavirus ocular ocular irritation ocular retention ophthalmic drug delivery outbreak penetration Polymer polymerized PPG provided RDV Remdesivir SARS-CoV-2 Spread temperature thermosensitive hydrogel Tolerance Transmission was used [DOI] 10.3390/pharmaceutics14010050 PMC 바로가기 [Article Type] Article
Polymer-based nano-therapies to combat COVID-19 related respiratory injury: progress, prospects, and challengesReview Article Published on 2021-04-142023-06-15 Journal: Journal of Biomaterials Science. Polymer Edition [Category] MERS, SARS, [키워드] ARDS COVID-19 hydrogel nanocarrier Polymer respiratory injury Scaffold tissue engineering [DOI] 10.1080/09205063.2021.1909412 PMC 바로가기 [Article Type] Review Article
3D Bioprinting of In Vitro Models Using Hydrogel-Based BioinksReview Published on 2021-01-242022-10-28 Journal: The British journal of oral & maxillofacial surger [Category] COVID-19, [키워드] 3D bioprinting 3D cell printing bioink biological function caused Coronavirus disease 2019 COVID-19 Diseases global pandemic help hydrogel in vitro in vitro model Model organ pathogen physical distancing representing respond therapeutic agents tissue tissue engineering [DOI] 10.3390/polym13030366 PMC 바로가기 [Article Type] Review
A rapid diagnosis of SARS-CoV-2 using DNA hydrogel formation on microfluidic poresArticle Published on 2021-01-182023-06-15 Journal: Biosensors & bioelectronics [Category] MERS, SARS, [키워드] COVID-19 hydrogel Microfluidics Micropores nucleic acid Rolling circle amplification [DOI] 10.1016/j.bios.2021.113005 PMC 바로가기 [Article Type] Article
Hydrogel particles improve detection of SARS-CoV-2 RNA from multiple sample types하이드로겔 입자는 여러 샘플 유형에서 SARS-CoV-2 RNA의 검출을 향상시킵니다.Article Published on 2020-12-302022-08-31 Journal: Scientific Reports [Category] MERS, SARS, 진단, 치료기술, 치료제, [키워드] average Biological techniques Biotechnology CDC Cycle threshold value diagnostic EUA hydrogel IMPROVE medium Microbiology nCoV nucleic acid nucleic acid extraction Particle Particles positive sample Qiagen real-time RT-PCR RNA extraction Saliva saliva samples SARS-CoV-2 SARS-CoV-2 RNA tested Transport transport medium Viral Viral load Viral RNA viral titer viral titers virus Volume [DOI] 10.1038/s41598-020-78771-8 PMC 바로가기 [Article Type] Article
Morphogenetic (Mucin Expression) as Well as Potential Anti-Corona Viral Activity of the Marine Secondary Metabolite Polyphosphate on A549 CellsA549 세포에 대한 해양 2차 대사산물 폴리포스페이트의 형태유전학적(뮤신 발현) 및 잠재적인 항-코로나 바이러스 활성Article Published on 2020-12-142022-09-10 Journal: Marine Drugs [Category] MERS, SARS, 바이오마커, [키워드] A549 A549 cell ACE2 receptor activity addition adenylate kinase ADK alkaline phosphatase ALP alveolar antiviral response ATP attachment Bacteria binding block Blood Blood platelets Bronchial epithelium Cell cell growth cells cellular collagen coronavirus coronavirus SARS-CoV-2 epithelial Express expression Extracellular extracellular ATP growth human alveolar cells hydrogel immunostaining in vitro in vivo Inhaled inhibiting Innate immunity involved metabolic energy MUC1 MUC5AC mucin mucins nasopharynx nontoxic pathogen Pathogens phosphatase physiological Platelets Polymer polyp polyphosphate Potential protective effect Proteins RBD Receptor binding domain reduction in released SARS-CoV-2 spike protein secondary secreted significantly increased stimulated strength the cells These cells Viral viral RBD virus well [DOI] 10.3390/md18120639 PMC 바로가기 [Article Type] Article